Abstract: Objective To understand the current situation of unintentional injuries among middle school students in China.Methods A total of 22 628 middle school students from thirty-three schools in six cities of China were selected by stratified cluster sampling method.Demographic characteristics and unintentional injuries was collected through questionnaire survey.Results The total detection rate of injury was 46.7%,male students (47.9%) higher than female students (45.6%),and the junior high school students (50.6%) higher than senior high school students (42.4%).The differences were statistically significant (x2=12.643,150.656,P<0.05).The most common types of unintentional injuries were abrasions or scrapes (29.4%),falling or tripping (19.7%) and stabbing or cutting (16.3%).Logistic regression analysis showed that junior middle school students,live in rural areas,physical activities and participation in sports teams were risk factors for unintentional injuries among middle school students(P< 0.05).The risk of unintentional injury among middle school students in economically developed areas was lower than that in less developed areas(x2=55.11,P<0.05).Conclusion The prevalence rate of unintentional injuries among Chinese middle school students in six cities is higher.The unintentional injuries are multifactorial,and priorities should be given to the different risk factors when establish the preventive measures.