Abstract: Children and adolescents belong to the group with high incidence of unintentional injury which is the main cause for the death on a global scale.Therefore,it is of great significance to improve the health level of the total population by focusing on unintentional injury in this group.This editorial at first presents the pervasiveness,severity and preventability of unintentional injury in children and adolescents,then states proposals as following:the priority for unintentional injury prevention and control falls on monitoring system establishment and monitoring method standardization;intensify the researches on unintentional injury disease burden;constitute prevention strategies and measures in line with local reality;increase prevention research and investment on unintentional injury.In general,this editorial aims to provide further research approaches and scientific basis for implementing the prevention and control of unintentional injury in children and adolescents.