Abstract: Advances in public health and social civilization have facilitated better understanding of benefits,roles,and responsibilities of school health in promoting child and adolescent health,as well as enabling them to reach their full health potential.This editorial starts with an updated concept of school health,gives a comprehensive overview on characteristics and social determinants of various stages across growth and development,proposes the life-course perspective as a theoretical framework for collective efforts to improve school health,with the aim to fully inspire and mobilize initiatives and creativities among children and adolescents,and to promote the integration of school health into all policies.A key message of this editorial is the need to invest widely,deeply,and effectively in child and adolescent health:from the first 1 000 days to holistic concern over the first 10 000 days,which provides a critical foundation of lifelong health and an unprecedented opportunity for a better tomorrow of school health.