摘要:
了解石家庄市鹿泉区中小学新生结核病感染情况,探索学校发现和预防肺结核的办法.方法 对鹿泉区2011-2015年51 528名中小学新生进行结核菌素试验(PPD),并分析其肺结核发病情况.结果 BCG-PPD组与TB-PPD组的阳性率及强阳性率差异均有统计学意义(x2值分别为58.424,13.995,P值均<0.05).不同年级学生PPD阳性率及强阳性率间差异有统计学意义(2011-2013年X2值分别为348.501,279.369,2014-2015年x2值分别为203.289,111.693,P值均<0.05).818名强阳性者进一步检查691名(84.47%).发现活动性肺结核高中生4名、初中生2名、无小学生,肺结核检出率为0.73%.420名强阳性者使用“母牛分支杆菌”双向免疫调节剂进行预防.结论 中学生结核分枝杆菌感染不容忽视,应将结核病筛查和结核病健康教育纳入学校的制度化管理.
关键词:
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结核,肺 /
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结核菌素试验 /
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疾病 /
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学生
Abstract:
Objective To understand tuberculosis infection situation among primary and secondary school students in Luquan district of Shijiazhuang,Hebei Province.Methods Purified protein derivative (PPD) skin test was performed in 51 528 students in primary and secondary schools in Luquan district of Shijiazhuang,tuberculosis infection was investigated at the same period.Results Significant differences were found in positive rate and strong positive rate between bacille Calmette-Guerin (BCG)-PPD and TB-PPD group.Different grade students differed in PPD positive rate and strong positive rate.Further examination was implemented among 691/818(84.47%) strong positive students.Four high school students and two junior school students were detected to be active tuberculosis patients.Prevalence of pulmonary tuberculosis was 0.73%.There were 61.31% (420) students reported using Mycobacterium vaccae (MV) in prevention of tuberculosis.Conclusion Middle school students are vulnerable population for mycobacterium tuberculosis infection.Tuberculosis screening and education should be included in the institutionalized management of the school.